Key Points
Question What are the pooled estimates from existing literature examining the association between hypertensive disorders of pregnancy and neurodevelopmental disorders in offspring?
Findings Pooled estimates from this systematic review and meta-analysis of 61 studies suggest that exposure to hypertensive disorders of pregnancy is associated with a small yet statistically significant increase in the odds of autism spectrum disorder and attention-deficit/hyperactivity disorder in offspring compared with no exposure.
Meaning Increased developmental screening of infants exposed to hypertensive disorders of pregnancy could allow for early intervention, which in turn may improve neurodevelopmental outcome.
