A drug normally used to increase the rate at which people urinate improves some of the symptoms of autism in children, according to a small clinical trial published today in Translational Psychiatry1. ---- In children taking bumetanide who were less severely affected by autism, the researchers saw small but significant improvements in behaviour. The drug also seemed to be safe and well tolerated with few side effects, they say. ---- She adds, however, that the effects of the drug were small, and that one-third of the placebo group also showed some amelioration of symptoms. “The effects were only noticeable on some gross behavioural measures, [but the findings are] consistent with my view that there is a lot of spontaneous fluctuation in symptoms and a general tendency to improve over time,” she adds. -----
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