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Thursday, December 2, 2010

Researchers one step closer to potential autism test

Scientists are finding more pieces of the autism puzzle of with the help of MRI scans of brain circuitry, according to a study published Thursday online in the journal Autism Research. By scanning the brain for 10 minutes using magnetic resonance imaging, researchers were able to measure six physical differences of microscopic fibers in the brains of 30 males with confirmed high-functioning autism and 30 males without autism. The images of the brains helped researchers correctly identify those with autism with 94 percent accuracy, says Nicholas Lange, an associate professor of psychiatry at Harvard Medical School and one of the study authors. "No one has measured what we measured," says Lange of the MRI test he and Dr. Janet Lainhart from the University of Utah developed. While previous studies using different types of scans have been able to identify people with autism, Lange says, "no one has looked at it [the brain] the way we have and no one has gotten these type of results." Lange is quick to caution that this type of test is not yet ready for prime time. "We do not want to give anyone false hopes that this is ready for the clinic yet. This method, this test, needs to be tried [and confirmed] with many more subjects outside our laboratory," he says. Plus, the research needs to be expanded to many more study participants and tried on younger people with autism and those who are not as high-functioning as the subjects in this first trial.
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